Unexplained Fertility: Gluten or Celiac?

Celiac disease, also known as gluten-sensitive enteropathy, is characterized by chronic intestinal malabsorption caused by intolerance to gluten. Gluten stimulates the immune system that results in increased permeability of the intestinal mucosa. This increased permeability can result in other grain and milk proteins to cross the intestinal mucosa, and cause the body to mount an immune response.

It typically involves the small intestine and usually presents in the first 3 years of life, but it may reappear again with the average age of onset being 35-40 years. Some of the common signs and symptoms are weight loss, multiple vitamin and mineral deficiencies, as well as bone density changes. In women with Celiac disease, there is an increase in the rates of miscarriages, infertility, and amenorrhea.